A UV–Induced Genetic Network Links the RSC Complex to Nucleotide Excision Repair and Shows Dose-Dependent Rewiring

Efficient repair of UV-induced DNA damage requires the precise coordination of nucleotide excision repair (NER) with numerous other biological processes. To map this crosstalk, we generated a differential genetic interaction map centered on quantitative growth measurements of >45,000 double mutan...

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Main Authors: Srivas, Rohith, Costelloe, Thomas, Carvunis, Anne-Ruxandra, Sarkar, Sovan, Malta, Erik, Sun, Su Ming, Pool, Marijke, Licon, Katherine, van Welsem, Tibor, van Leeuwen, Fred, McHugh, Peter J., van Attikum, Haico, Ideker, Trey
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136507/
https://ncbi.nlm.nih.gov/pubmed/24360959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.11.035
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