The Enterovirus Protease Inhibitor Rupintrivir Exerts Cross-Genotypic Anti-Norovirus Activity and Clears Cells from the Norovirus Replicon

Potent and safe inhibitors of norovirus replication are needed for the treatment and prophylaxis of norovirus infections. We here report that the in vitro anti-norovirus activity of the protease inhibitor rupintrivir is extended to murine noroviruses and that rupintrivir clears human cells from thei...

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Autores principales: Rocha-Pereira, J., Nascimento, M. S. J., Ma, Q., Hilgenfeld, R., Neyts, J., Jochmans, D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136040/
https://ncbi.nlm.nih.gov/pubmed/24890597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02546-13
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