The Enterovirus Protease Inhibitor Rupintrivir Exerts Cross-Genotypic Anti-Norovirus Activity and Clears Cells from the Norovirus Replicon

Potent and safe inhibitors of norovirus replication are needed for the treatment and prophylaxis of norovirus infections. We here report that the in vitro anti-norovirus activity of the protease inhibitor rupintrivir is extended to murine noroviruses and that rupintrivir clears human cells from thei...

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Bibliographic Details
Main Authors: Rocha-Pereira, J., Nascimento, M. S. J., Ma, Q., Hilgenfeld, R., Neyts, J., Jochmans, D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136040/
https://ncbi.nlm.nih.gov/pubmed/24890597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02546-13
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