Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues

EV71 is the primary pathogenic cause of hand-foot-mouth disease (HFMD), but an effective antiviral drug currently is unavailable. Rupintrivir, an inhibitor against human rhinovirus (HRV), has potent antiviral activities against EV71. We determined the high-resolution crystal structures of the EV71 3...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wang, Jing, Fan, Tingting, Yao, Xue, Wu, Zhiqiang, Guo, Li, Lei, Xiaobo, Wang, Jianwei, Wang, Meitian, Jin, Qi, Cui, Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196404/
https://ncbi.nlm.nih.gov/pubmed/21813612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05107-11
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados