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Association between pncA Gene Mutations, Pyrazinamidase Activity, and Pyrazinamide Susceptibility Testing in Mycobacterium tuberculosis

We determined MICs for, confirmed the presence of pncA mutations in, and performed pyrazinamidase testing on colonies (subclones) obtained from seven isolates that exhibited differential pyrazinamide (PZA) susceptibility. Six of the seven strains were found to exhibit characteristics resulting from...

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Библиографические подробности
Главные авторы: Aono, Akio, Chikamatsu, Kinuyo, Yamada, Hiroyuki, Kato, Tomoko, Mitarai, Satoshi
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136016/
https://ncbi.nlm.nih.gov/pubmed/24867972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02394-14
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