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Association between pncA Gene Mutations, Pyrazinamidase Activity, and Pyrazinamide Susceptibility Testing in Mycobacterium tuberculosis

We determined MICs for, confirmed the presence of pncA mutations in, and performed pyrazinamidase testing on colonies (subclones) obtained from seven isolates that exhibited differential pyrazinamide (PZA) susceptibility. Six of the seven strains were found to exhibit characteristics resulting from...

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Main Authors: Aono, Akio, Chikamatsu, Kinuyo, Yamada, Hiroyuki, Kato, Tomoko, Mitarai, Satoshi
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136016/
https://ncbi.nlm.nih.gov/pubmed/24867972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02394-14
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