pncA Mutations in Pyrazinamide-Resistant Mycobacterium tuberculosis Isolates in Portugal

The nucleotide sequences of the pncA genes within 55 multidrug-resistant pyrazinamide-resistant Mycobacterium tuberculosis clinical isolates were determined. Fifty-three out of the 55 isolates were pyrazinamidase (PZase) negative. Four strains contained a wild-type pncA gene, and PZase activity was...

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Autores principales: Portugal, Isabel, Barreiro, Luís, Moniz-Pereira, José, Brum, Laura
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC434191/
https://ncbi.nlm.nih.gov/pubmed/15215139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.7.2736-2738.2004
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