pncA Mutations in Pyrazinamide-Resistant Mycobacterium tuberculosis Isolates in Portugal

The nucleotide sequences of the pncA genes within 55 multidrug-resistant pyrazinamide-resistant Mycobacterium tuberculosis clinical isolates were determined. Fifty-three out of the 55 isolates were pyrazinamidase (PZase) negative. Four strains contained a wild-type pncA gene, and PZase activity was...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Portugal, Isabel, Barreiro, Luís, Moniz-Pereira, José, Brum, Laura
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2004
Sujets:	Mechanisms of Resistance
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434191/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15215139/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.7.2736-2738.2004
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