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Placental Transfer of Darunavir in an Ex Vivo Human Cotyledon Perfusion Model
Placental transfer of the HIV protease inhibitor darunavir was investigated in 5 term human cotyledons perfused with darunavir (1,000 ng/ml) in the maternal to fetal direction. The mean (± the standard deviation [SD]) fetal transfer rate (FTR) (fetal/maternal concentration at steady state from 30 to...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135808/ https://ncbi.nlm.nih.gov/pubmed/24982090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03184-14 |
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