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Placental Transfer of Darunavir in an Ex Vivo Human Cotyledon Perfusion Model

Placental transfer of the HIV protease inhibitor darunavir was investigated in 5 term human cotyledons perfused with darunavir (1,000 ng/ml) in the maternal to fetal direction. The mean (± the standard deviation [SD]) fetal transfer rate (FTR) (fetal/maternal concentration at steady state from 30 to...

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Hlavní autoři: Mandelbrot, Laurent, Duro, Dominique, Belissa, Emilie, Peytavin, Gilles
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135808/
https://ncbi.nlm.nih.gov/pubmed/24982090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03184-14
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