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Bidirectional Transfer of Raltegravir in an Ex Vivo Human Cotyledon Perfusion Model
Placental transfer of the HIV integrase inhibitor raltegravir (RLT) was investigated in term human cotyledons in the maternal-to-fetal (n = 3) and fetal-to-maternal (n = 6) directions. In the maternal-to-fetal direction, the mean ± standard deviation (SD) fetal transfer rate (FTR) was 9.1% ± 1.4%, a...
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| Gepubliceerd in: | Antimicrob Agents Chemother |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862479/ https://ncbi.nlm.nih.gov/pubmed/26833154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00007-16 |
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