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DETECTION OF THE BRAF V600E MUTATION IN COLON CARCINOMA – CRITICAL EVALUATION OF THE IMUNOHISTOCHEMICAL APPROACH

Recently BRAF V600E mutant-specific antibody (clone VE1) became available to immunohistochemically pinpoint the occurrence of these BRAF mutant proteins in different tumors, such as colon carcinoma. Detection of BRAF mutations is important for the accurate application of targeted therapy against BRA...

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Autors principals: Lasota, Jerzy, Kowalik, Artur, Wasag, Bartek, Wang, Zeng-Feng, Felisiak-Golabek, Anna, Coates, Tiffany, Kopczynski, Janusz, Gozdz, Stanislaw, Miettinen, Markku
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134735/
https://ncbi.nlm.nih.gov/pubmed/24832158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000000229
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