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DETECTION OF THE BRAF V600E MUTATION IN COLON CARCINOMA – CRITICAL EVALUATION OF THE IMUNOHISTOCHEMICAL APPROACH

Recently BRAF V600E mutant-specific antibody (clone VE1) became available to immunohistochemically pinpoint the occurrence of these BRAF mutant proteins in different tumors, such as colon carcinoma. Detection of BRAF mutations is important for the accurate application of targeted therapy against BRA...

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Detalhes bibliográficos
Main Authors: Lasota, Jerzy, Kowalik, Artur, Wasag, Bartek, Wang, Zeng-Feng, Felisiak-Golabek, Anna, Coates, Tiffany, Kopczynski, Janusz, Gozdz, Stanislaw, Miettinen, Markku
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134735/
https://ncbi.nlm.nih.gov/pubmed/24832158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000000229
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