DETECTION OF THE BRAF V600E MUTATION IN COLON CARCINOMA – CRITICAL EVALUATION OF THE IMUNOHISTOCHEMICAL APPROACH

Recently BRAF V600E mutant-specific antibody (clone VE1) became available to immunohistochemically pinpoint the occurrence of these BRAF mutant proteins in different tumors, such as colon carcinoma. Detection of BRAF mutations is important for the accurate application of targeted therapy against BRA...

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Bibliographic Details
Main Authors:	Lasota, Jerzy, Kowalik, Artur, Wasag, Bartek, Wang, Zeng-Feng, Felisiak-Golabek, Anna, Coates, Tiffany, Kopczynski, Janusz, Gozdz, Stanislaw, Miettinen, Markku
Format:	Artigo
Language:	Inglês
Published:	2014
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4134735/ https://ncbi.nlm.nih.gov/pubmed/24832158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000000229
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DETECTION OF THE BRAF V600E MUTATION IN COLON CARCINOMA – CRITICAL EVALUATION OF THE IMUNOHISTOCHEMICAL APPROACH

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