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Low activity of select Hsp104 mutants is sufficient to propagate unstable prion variants
The molecular chaperone network plays a critical role in the formation and propagation of self-replicating yeast prions. Not only do individual prions differ in their requirements for certain chaperones, but structural variants of the same prion can also display distinct dependences on the chaperone...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Landes Bioscience
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4134344/ https://ncbi.nlm.nih.gov/pubmed/24064980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.26547 |
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