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Importance of low-oligomeric-weight species for prion propagation in the yeast prion system Sup35/Hsp104

The [PSI(+)] determinant of Saccharomyces cerevisiae, consisting of the cytosolic translation termination factor Sup35, is a prion-type genetic element that induces an inheritable conformational change and converts the Sup35 protein into amyloid fibers. The molecular chaperone Hsp104 is required to...

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Detalhes bibliográficos
Main Authors: Narayanan, Saravanakumar, Bösl, Benjamin, Walter, Stefan, Reif, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC170910/
https://ncbi.nlm.nih.gov/pubmed/12876196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1233535100
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