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Importance of low-oligomeric-weight species for prion propagation in the yeast prion system Sup35/Hsp104

The [PSI(+)] determinant of Saccharomyces cerevisiae, consisting of the cytosolic translation termination factor Sup35, is a prion-type genetic element that induces an inheritable conformational change and converts the Sup35 protein into amyloid fibers. The molecular chaperone Hsp104 is required to...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Narayanan, Saravanakumar, Bösl, Benjamin, Walter, Stefan, Reif, Bernd
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2003
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC170910/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12876196/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1233535100
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