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Importance of low-oligomeric-weight species for prion propagation in the yeast prion system Sup35/Hsp104
The [PSI(+)] determinant of Saccharomyces cerevisiae, consisting of the cytosolic translation termination factor Sup35, is a prion-type genetic element that induces an inheritable conformational change and converts the Sup35 protein into amyloid fibers. The molecular chaperone Hsp104 is required to...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC170910/ https://ncbi.nlm.nih.gov/pubmed/12876196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1233535100 |
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