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Low activity of select Hsp104 mutants is sufficient to propagate unstable prion variants

The molecular chaperone network plays a critical role in the formation and propagation of self-replicating yeast prions. Not only do individual prions differ in their requirements for certain chaperones, but structural variants of the same prion can also display distinct dependences on the chaperone...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dulle, Jennifer E, True, Heather L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134344/
https://ncbi.nlm.nih.gov/pubmed/24064980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.26547
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