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Low activity of select Hsp104 mutants is sufficient to propagate unstable prion variants

The molecular chaperone network plays a critical role in the formation and propagation of self-replicating yeast prions. Not only do individual prions differ in their requirements for certain chaperones, but structural variants of the same prion can also display distinct dependences on the chaperone...

詳細記述

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書誌詳細
主要な著者: Dulle, Jennifer E, True, Heather L
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134344/
https://ncbi.nlm.nih.gov/pubmed/24064980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.26547
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