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Assessing the causes and consequences of co-polymerization in amyloid formation

How, and why, different proteins form amyloid fibrils is most often studied in vitro using a single purified protein sequence. However, many amyloid diseases involve co-aggregation of different protein species, including proteins with/without post-translational modifications (e.g., different strains...

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Bibliographic Details
Main Authors: Sarell, Claire J, Stockley, Peter G, Radford, Sheena E
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134340/
https://ncbi.nlm.nih.gov/pubmed/24025483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.26415
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