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Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers

Although amyloid assembly in vitro is commonly investigated using single protein sequences, fibril formation in vivo can be more heterogeneous, involving co-assembly of proteins of different length, sequence and/or post-translational modifications. Emerging evidence suggests that co-polymerization c...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Chem Sci
Päätekijät: Young, Lydia M., Tu, Ling-Hsien, Raleigh, Daniel P., Ashcroft, Alison E., Radford, Sheena E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Royal Society of Chemistry 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613229/
https://ncbi.nlm.nih.gov/pubmed/28970890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc00620a
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