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Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers

Although amyloid assembly in vitro is commonly investigated using single protein sequences, fibril formation in vivo can be more heterogeneous, involving co-assembly of proteins of different length, sequence and/or post-translational modifications. Emerging evidence suggests that co-polymerization c...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Young, Lydia M., Tu, Ling-Hsien, Raleigh, Daniel P., Ashcroft, Alison E., Radford, Sheena E.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613229/
https://ncbi.nlm.nih.gov/pubmed/28970890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc00620a
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