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True and apparent inhibition of amyloid fibril formation

A possible therapeutic strategy for amyloid diseases involves the use of small molecule compounds to inhibit protein assembly into insoluble aggregates. According to the recently proposed Crystallization-Like Model, the kinetics of amyloid fibrillization can be retarded by decreasing the frequency o...

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Detalhes bibliográficos
Autor principal: Martins, Pedro M.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609120/
https://ncbi.nlm.nih.gov/pubmed/23232498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.23111
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