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A- and B-type cyclins differentially modulate substrate specificity of cyclin-cdk complexes.

Both cyclins A and B associate with and thereby activate cyclin-dependent protein kinases (cdks). We have investigated which component in the cyclin-cdk complex determines its substrate specificity. The A- and B-type cyclin-cdk complexes phosphorylated histone H1 and their cyclin subunits in an indi...

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Библиографические подробности
Главные авторы: Peeper, D S, Parker, L L, Ewen, M E, Toebes, M, Hall, F L, Xu, M, Zantema, A, van der Eb, A J, Piwnica-Worms, H
Формат: Artigo
Язык:Inglês
Опубликовано: 1993
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC413416/
https://ncbi.nlm.nih.gov/pubmed/8491188
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