A- and B-type cyclins differentially modulate substrate specificity of cyclin-cdk complexes.

Both cyclins A and B associate with and thereby activate cyclin-dependent protein kinases (cdks). We have investigated which component in the cyclin-cdk complex determines its substrate specificity. The A- and B-type cyclin-cdk complexes phosphorylated histone H1 and their cyclin subunits in an indi...

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Pubblicato in:	EMBO J
Autori principali:	Peeper, D S, Parker, L L, Ewen, M E, Toebes, M, Hall, F L, Xu, M, Zantema, A, van der Eb, A J, Piwnica-Worms, H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413416/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8491188/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05844.x
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