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PIDD mediates and stabilizes the interaction between RAIDD and Caspase-2 for the PIDDosome assembly
The PIDDosome, which is an oligomeric signaling complex composed of PIDD, RAIDD and caspase-2, can induce proximity-based dimerization and activation of caspase-2. In the PIDDosome assembly, the adaptor protein RAIDD interacts with PIDD and caspase-2 via CARD:CARD and DD:DD, respectively. To analyze...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Korean Society for Biochemistry and Molecular Biology
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133880/ https://ncbi.nlm.nih.gov/pubmed/24064063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2013.46.9.021 |
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