PIDD mediates and stabilizes the interaction between RAIDD and Caspase-2 for the PIDDosome assembly

The PIDDosome, which is an oligomeric signaling complex composed of PIDD, RAIDD and caspase-2, can induce proximity-based dimerization and activation of caspase-2. In the PIDDosome assembly, the adaptor protein RAIDD interacts with PIDD and caspase-2 via CARD:CARD and DD:DD, respectively. To analyze...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Jang, Tae-ho, Park, Hyun Ho
Materialtyp: Artigo
Språk:Inglês
Publicerad: Korean Society for Biochemistry and Molecular Biology 2013
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133880/
https://ncbi.nlm.nih.gov/pubmed/24064063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2013.46.9.021
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