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PIDD mediates and stabilizes the interaction between RAIDD and Caspase-2 for the PIDDosome assembly
The PIDDosome, which is an oligomeric signaling complexcomposed of PIDD, RAIDD and caspase-2, can induceproximity-based dimerization and activation of caspase-2. Inthe PIDDosome assembly, the adaptor protein RAIDDinteracts with PIDD and caspase-2 via CARD:CARD andDD:DD, respectively. To analyze the...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Korean Society for Biochemistry and Molecular Biology
2013-09-01
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| Colecção: | BMB Reports |
| Assuntos: | |
| Acesso em linha: | http://bmbreports.org/jbmb/pdf.php?data=MTMxMDA3MTZAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0Ni05JTVEMTMwOTI2MTczNF8lMjg0NzEtNDc2JTI5Qk1CXzEzLTAyMS5wZGY= |
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