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Neuronal caspase 2 activity and function requires RAIDD, but not PIDD

Caspase 2 was initially identified as a neuronally expressed developmentally down-regulated gene (HUGO gene nomenclature CASP2) and has been shown to be required for neuronal death induced by several stimuli, including NGF (nerve growth factor) deprivation and Aβ (β-amyloid). In non-neuronal cells t...

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Detalhes bibliográficos
Main Authors: Ribe, Elena M., Jean, Ying Y., Goldstein, Rebecca L., Manzl, Claudia, Stefanis, Leonidas, Villunger, Andreas, Troy, Carol M.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365438/
https://ncbi.nlm.nih.gov/pubmed/22515271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111588
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