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In vitro Reconstitution of the Interactions in the PIDDosome

Caspase-2 is critical for genotoxic stress induced apoptosis and is activated by formation of the PIDDosome, an oligomeric caspase-2 activating complex. The PIDDosome comprises three protein components, PIDD, RAIDD and caspase-2. RAIDD contains both a death domain (DD) and a caspase recruitment doma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jang, Tae-ho, Zheng, Chao, Wu, Hao, Jeon, Ju-Hong, Park, Hyun Ho
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062965/
https://ncbi.nlm.nih.gov/pubmed/20872280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-010-0544-2
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