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In vitro Reconstitution of the Interactions in the PIDDosome
Caspase-2 is critical for genotoxic stress induced apoptosis and is activated by formation of the PIDDosome, an oligomeric caspase-2 activating complex. The PIDDosome comprises three protein components, PIDD, RAIDD and caspase-2. RAIDD contains both a death domain (DD) and a caspase recruitment doma...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062965/ https://ncbi.nlm.nih.gov/pubmed/20872280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-010-0544-2 |
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