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In vitro Reconstitution of the Interactions in the PIDDosome

Caspase-2 is critical for genotoxic stress induced apoptosis and is activated by formation of the PIDDosome, an oligomeric caspase-2 activating complex. The PIDDosome comprises three protein components, PIDD, RAIDD and caspase-2. RAIDD contains both a death domain (DD) and a caspase recruitment doma...

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Sonraí Bibleagrafaíochta
Main Authors: Jang, Tae-ho, Zheng, Chao, Wu, Hao, Jeon, Ju-Hong, Park, Hyun Ho
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062965/
https://ncbi.nlm.nih.gov/pubmed/20872280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-010-0544-2
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