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Structure-function analysis of human IL-6 receptor: dissociation of amino acid residues required for IL-6-binding and for IL-6 signal transduction through gp130.

Here, we report the analysis of the structure-function relationship of the extracellular region of human interleukin 6 receptor (IL-6R). Upon binding of IL-6, IL-6R becomes associated extracellularly with a non-IL-6-binding but signal transducing molecule, gp130, and the IL-6 signal is generated. In...

詳細記述

保存先:
書誌詳細
主要な著者: Yawata, H, Yasukawa, K, Natsuka, S, Murakami, M, Yamasaki, K, Hibi, M, Taga, T, Kishimoto, T
フォーマット: Artigo
言語:Inglês
出版事項: 1993
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC413384/
https://ncbi.nlm.nih.gov/pubmed/8467812
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