Echinomycin protects mice against relapsed acute myeloid leukemia without adverse effect on hematopoietic stem cells

Acute myeloid leukemia (AML) often relapses following chemotherapy-induced remission and is generally chemo-resistant. Given the potential role for cancer stem cells in relapse, targeting of the leukemia-initiating cell (LIC) in AML may provide improved outcome following remission induction. However...

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Detalhes bibliográficos
Main Authors: Wang, Yin, Liu, Yan, Tang, Fei, Bernot, Kelsie M., Schore, Reuven, Marcucci, Guido, Caligiuri, Michael A., Zheng, Pan, Liu, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133485/
https://ncbi.nlm.nih.gov/pubmed/24994068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-12-544221
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