Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL

One major goal of cancer genome sequencing is to identify key genes and pathways that drive tumor pathogenesis. Although many studies have identified candidate driver genes based on recurrence of mutations in individual genes, subsets of genes with nonrecurrent mutations may also be defined as putat...

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Bibliografiske detaljer
Main Authors: Wang, Lili, Shalek, Alex K., Lawrence, Mike, Ding, Ruihua, Gaublomme, Jellert T., Pochet, Nathalie, Stojanov, Petar, Sougnez, Carrie, Shukla, Sachet A., Stevenson, Kristen E., Zhang, Wandi, Wong, Jessica, Sievers, Quinlan L., MacDonald, Bryan T., Vartanov, Alexander R., Goldstein, Natalie R., Neuberg, Donna, He, Xi, Lander, Eric, Hacohen, Nir, Regev, Aviv, Getz, Gad, Brown, Jennifer R., Park, Hongkun, Wu, Catherine J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2014
Fag:
Lymphoid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133483/
https://ncbi.nlm.nih.gov/pubmed/24778153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-552067
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