Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL

One major goal of cancer genome sequencing is to identify key genes and pathways that drive tumor pathogenesis. Although many studies have identified candidate driver genes based on recurrence of mutations in individual genes, subsets of genes with nonrecurrent mutations may also be defined as putat...

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Detalhes bibliográficos
Main Authors: Wang, Lili, Shalek, Alex K., Lawrence, Mike, Ding, Ruihua, Gaublomme, Jellert T., Pochet, Nathalie, Stojanov, Petar, Sougnez, Carrie, Shukla, Sachet A., Stevenson, Kristen E., Zhang, Wandi, Wong, Jessica, Sievers, Quinlan L., MacDonald, Bryan T., Vartanov, Alexander R., Goldstein, Natalie R., Neuberg, Donna, He, Xi, Lander, Eric, Hacohen, Nir, Regev, Aviv, Getz, Gad, Brown, Jennifer R., Park, Hongkun, Wu, Catherine J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133483/
https://ncbi.nlm.nih.gov/pubmed/24778153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-552067
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