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Single-cell Genomics Unveils Critical Regulators of Th17 cell Pathogenicity
Extensive cellular heterogeneity exists within specific immune-cell subtypes classified as a single lineage, but its molecular underpinnings are rarely characterized at a genomic scale. Here, we use single-cell RNA-seq to investigate the molecular mechanisms governing heterogeneity and pathogenicity...
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| Опубликовано в: : | Cell |
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| Главные авторы: | , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4671824/ https://ncbi.nlm.nih.gov/pubmed/26607794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.11.009 |
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