Histone Deacetylase Inhibitors Impair the Elimination of HIV-Infected Cells by Cytotoxic T-Lymphocytes

Resting memory CD4(+) T-cells harboring latent HIV proviruses represent a critical barrier to viral eradication. Histone deacetylase inhibitors (HDACis), such as suberanilohydroxamic acid (SAHA), romidepsin, and panobinostat have been shown to induce HIV expression in these resting cells. Recently,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jones, Richard Brad, O'Connor, Rachel, Mueller, Stefanie, Foley, Maria, Szeto, Gregory L., Karel, Dan, Lichterfeld, Mathias, Kovacs, Colin, Ostrowski, Mario A., Trocha, Alicja, Irvine, Darrell J., Walker, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133386/
https://ncbi.nlm.nih.gov/pubmed/25122219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004287
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados