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A Structural and Biochemical Model of Processive Chitin Synthesis

Chitin synthases (CHS) produce chitin, an essential component of the fungal cell wall. The molecular mechanism of processive chitin synthesis is not understood, limiting the discovery of new inhibitors of this enzyme class. We identified the bacterial glycosyltransferase NodC as an appropriate model...

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Main Authors: Dorfmueller, Helge C., Ferenbach, Andrew T., Borodkin, Vladimir S., van Aalten, Daan M. F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132801/
https://ncbi.nlm.nih.gov/pubmed/24942743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563353
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