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A Structural and Biochemical Model of Processive Chitin Synthesis

Chitin synthases (CHS) produce chitin, an essential component of the fungal cell wall. The molecular mechanism of processive chitin synthesis is not understood, limiting the discovery of new inhibitors of this enzyme class. We identified the bacterial glycosyltransferase NodC as an appropriate model...

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Hlavní autoři: Dorfmueller, Helge C., Ferenbach, Andrew T., Borodkin, Vladimir S., van Aalten, Daan M. F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132801/
https://ncbi.nlm.nih.gov/pubmed/24942743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563353
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