Φορτώνει......
Unstable Reaction Intermediates and Hysteresis during the Catalytic Cycle of 5-Aminolevulinate Synthase: IMPLICATIONS FROM USING PSEUDO AND ALTERNATE SUBSTRATES AND A PROMISCUOUS ENZYME VARIANT
5-Aminolevulinate (ALA), an essential metabolite in all heme-synthesizing organisms, results from the pyridoxal 5′-phosphate (PLP)-dependent enzymatic condensation of glycine with succinyl-CoA in non-plant eukaryotes and α-proteobacteria. The predicted chemical mechanism of this ALA synthase (ALAS)-...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Biochemistry and Molecular Biology
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4132793/ https://ncbi.nlm.nih.gov/pubmed/24920668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.574731 |
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