Synthetic human beta-globin 5'HS2 constructs function as locus control regions only in multicopy transgene concatamers.

Transgenes linked to the beta-globin locus control region (LCR) are transcribed in a copy-dependent manner that is independent of the integration site. It has previously been shown that the LCR 5'HS2 region does not require its NF-E2 dimer binding site for LCR activity. In this paper we analyse...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Ellis, J, Talbot, D, Dillon, N, Grosveld, F
Формат: Artigo
Язык:Inglês
Опубликовано: 1993
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC413182/
https://ncbi.nlm.nih.gov/pubmed/8428573
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы