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β-arrestin-2-biased agonism of delta opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) in primary sensory neurons

Despite advances in understanding the signaling mechanisms involved in the development and maintenance of chronic pain, the pharmacologic treatment of chronic pain has seen little advancement. Agonists at the mu opioid receptor (MOPr) continue to be vital in the treatment of many forms of chronic pa...

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書誌詳細
主要な著者: Rowan, Matthew P, Szteyn, Kalina, Doyle, Allison P, Gomez, Ruben, Henry, Michael A, Jeske, Nathaniel A
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131480/
https://ncbi.nlm.nih.gov/pubmed/25085415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-10-50
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