β-Arrestin-2 Desensitizes the Transient Receptor Potential Vanilloid 1 (TRPV1) Channel

Transient receptor potential vanilloid 1 (TRPV1) is a nonselective cation channel activated by multiple stimuli and is implicated in a variety of pain disorders. Dynamic sensitization of TRPV1 activity by A-kinase anchoring protein 150 demonstrates a critical role for scaffolding proteins in nocicep...

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Detalhes bibliográficos
Main Authors: Por, Elaine D., Bierbower, Sonya M., Berg, Kelly A., Gomez, Ruben, Akopian, Armen N., Wetsel, William C., Jeske, Nathaniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481349/
https://ncbi.nlm.nih.gov/pubmed/22952227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.391847
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