βarrestin1-biased agonism at human δ-opioid receptor by peptidic and alkaloid ligands

We have previously reported on the differential regulation of the human δ-opioid receptor (hDOR) by alkaloid (etorphine) and peptidic (DPDPE and deltorphin I) ligands, in terms of both receptor desensitization and post-endocytic sorting. Since βarrestins are well known to regulate G protein-coupled...

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Main Authors: Aguila, Benjamin, Coulbault, Laurent, Davis, Audrey, Marie, Nicolas, Hasbi, Ahmed, Le bras, Florian, Tóth, Géza, Borsodi, Anna, Gurevich, Vsevolod V., Jauzac, Philippe, Allouche, Stéphane
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392209/
https://ncbi.nlm.nih.gov/pubmed/22101011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.10.018
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