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β-Arrestin–Biased Agonism of the Angiotensin Receptor Induced by Mechanical Stress
β-Arrestins, which were originally characterized as terminators of heterotrimeric guanine nucleotide–binding protein (G protein)–coupled receptor (GPCR) signaling, also act as important signal transducers. An emerging concept in GPCR signaling is β-arrestin–biased agonism, in which specific ligand-a...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2981501/ https://ncbi.nlm.nih.gov/pubmed/20530803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000769 |
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