β-Arrestin-biased AT1R stimulation promotes cell survival during acute cardiac injury

Pharmacological blockade of the ANG II type 1 receptor (AT1R) is a common therapy for treatment of congestive heart failure and hypertension. Increasing evidence suggests that selective engagement of β-arrestin-mediated AT1R signaling, referred to as biased signaling, promotes cardioprotective signa...

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Detalhes bibliográficos
Main Authors: Kim, Ki-Seok, Abraham, Dennis, Williams, Barbara, Violin, Jonathan D., Mao, Lan, Rockman, Howard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Cardiovascular Neurohormonal Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469643/
https://ncbi.nlm.nih.gov/pubmed/22886417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00475.2012
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