β-arrestin-biased agonism of β-adrenergic receptor regulates Dicer-mediated microRNA maturation to promote cardioprotective signaling

RATIONALE: MicroRNAs (miRs) are small, non-coding RNAs that function to post-transcriptionally regulate target genes. First transcribed as primary miR transcripts (pri-miRs), they are enzymatically processed by Drosha into premature miRs (pre-miRs) and further cleaved by Dicer into mature miRs. Init...

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Publicado no:J Mol Cell Cardiol
Main Authors: Teoh, Jian-peng, Bayoumi, Ahmed S., Aonuma, Tatsuya, Xu, Yanyan, Johnson, John A., Su, Huabo, Weintraub, Neal L., Tang, Yaoliang, Kim, Il-man
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940519/
https://ncbi.nlm.nih.gov/pubmed/29627294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.04.001
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