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Aneuploidy in pluripotent stem cells and implications for cancerous transformation

Owing to a unique set of attributes, human pluripotent stem cells (hPSCs) have emerged as a promising cell source for regenerative medicine, disease modeling and drug discovery. Assurance of genetic stability over long term maintenance of hPSCs is pivotal in this endeavor, but hPSCs can adapt to lif...

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Detalhes bibliográficos
Main Authors: Na, Jie, Baker, Duncan, Zhang, Jing, Andrews, Peter W., Barbaric, Ivana
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130921/
https://ncbi.nlm.nih.gov/pubmed/24899134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-014-0073-9
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