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Aneuploidy in pluripotent stem cells and implications for cancerous transformation

Owing to a unique set of attributes, human pluripotent stem cells (hPSCs) have emerged as a promising cell source for regenerative medicine, disease modeling and drug discovery. Assurance of genetic stability over long term maintenance of hPSCs is pivotal in this endeavor, but hPSCs can adapt to lif...

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Autors principals: Na, Jie, Baker, Duncan, Zhang, Jing, Andrews, Peter W., Barbaric, Ivana
Format: Artigo
Idioma:Inglês
Publicat: Higher Education Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130921/
https://ncbi.nlm.nih.gov/pubmed/24899134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-014-0073-9
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