Aneuploidy is permissive for hepatocyte-like cell differentiation from human induced pluripotent stem cells

BACKGROUND: The characterization of induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs) routinely includes analyses of chromosomal integrity. The belief is that pluripotent stem cells best suited to the generation of differentiated derivatives should display a euploid karyotype; a...

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Autores principales: Noto, Fallon K, Determan, Megan R, Cai, Jun, Cayo, Max A, Mallanna, Sunil K, Duncan, Stephen A
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105394/
https://ncbi.nlm.nih.gov/pubmed/25002137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-437
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