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Aneuploidy is permissive for hepatocyte-like cell differentiation from human induced pluripotent stem cells

BACKGROUND: The characterization of induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs) routinely includes analyses of chromosomal integrity. The belief is that pluripotent stem cells best suited to the generation of differentiated derivatives should display a euploid karyotype; a...

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Détails bibliographiques
Auteurs principaux: Noto, Fallon K, Determan, Megan R, Cai, Jun, Cayo, Max A, Mallanna, Sunil K, Duncan, Stephen A
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105394/
https://ncbi.nlm.nih.gov/pubmed/25002137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-437
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