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Discovery libraries targeting the major enzyme classes: the serine hydrolases

Two libraries of modestly reactive ureas containing either electron-deficient acyl anilines or acyl pyrazoles were prepared and are reported as screening libraries for candidate serine hydrolase inhibitors. Within each library is a small but powerful subset of compounds that serve as a chemotype fra...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Otrubova, Katerina, Srinivasan, Venkat, Boger, Dale L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130767/
https://ncbi.nlm.nih.gov/pubmed/25037918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.06.063
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